EDITORIAL AND ANNOUNCEMENTS
Breaking Ranks  ... 45-46
Announcement  ... 47

RESEARCH REPORTS
Effects of fluoride on mechanical properties of femoral bone in growing rats
  A Bohatyrewicz, Poland ... 47-54

Epidemiological and radiological study of skeletal fluorosis in Minzhu Town,
Longli County, Guizhou Province, China
  Dasheng Li, Rongxiang Duan,
  Shuquan Wang, Guangyu He,
  Ping Li, Zhongxue Nie,
  Tongan Wen, China ... 55-59

Effect of heat stress and high fluoride intake on gastrointestinal function in healthy humans
  K Sridharan, TN Upadhyay,
  AK Mukherjee, MML Kumria,
  SKB Patil, PK Ghosh, NK Madan,
  Ram Gopal, India ... 60-66

Some observations on fluoride problems in the Moldova Republic
  S Toma, J Kreidman,
  O Vedina, S Veliksar,
  Moldova and USA ... 67-70

Fluoride distribution in Burozems of Moldova
  O Vedina and J Kreidman,
  USA and Moldova ... 71-73

Accumulation of fluoride in plants exposed to geothermal and industrial water
  GW Miller, JL Shupe,
  OT Vedina, U.S.A. ... 74-83

Separation of interfering elements from commercial phosphoric acid for titrimetric determination of fluoride
  R Al-Merey, Z Hariri, Syria ... 84-90

The impact of water-borne fluoride on bone density
  W Czarnowski, J Krechniak,
  B Urbańska, K Stolarska,
  M Taraszewska-Czarnowska,
  A Muraszko-Klaudel,
  Poland ... 91-95

ABSTRACTS

BIOCHEMICAL EFFECTS
Sevoflurane: metabolism and toxicity [German]
  M Nuscheler, P Conzen, K Peter,
  Germany ... 96

First experimental evidence for human dentine crystal formation involving conversion of octacalcium phosphate to hydroxyapatite
  P Bodier-Houlle, P Steuer,
  JC Voegel, FJG Cuisinier,
  France ... 96-97

Halothane attenuates calcium sensitization in airway smooth muscle by inhibiting G-proteins
  T Kai, KA Jones, DO Warner,
  USA ... 97-98

Cytogenetic effects on lymphocytes in osteoporotic patients on long-term fluoride therapy
  P van Asten, F Darroudi,
  T Natarajan, IJ Terpstra,
  SA Duursma, Netherlands ... 98

Nanocrystals of magnesium and fluoride substituted hydroxyapatite
  E Bertoni, A Bigi, G Cojazzi,
  M Gandolfi, S Panzavolta,
  N Roveri, Italy ... 98-99

Are there strong hydrogen bonds in aqueous solutions?
  PA Frey, WW Cleland,
  USA ... 99-100

Heterotrimeric g proteins as fluoride targets in bone (review)
  M Susa, Switzerland ... 100-101

Microscopic hydration of the fluoride anion
  OM Cabarcos, CJ Weinheimer,
  JM Lisy, SS Xantheas, USA ... 101

Electron localization function view of bonding in selected aluminum fluoride molecules
  L Joubert, G Picard, B Silvi,
  F Fuster, France ... 101-102

G-proteins are involved in 5-HT receptor-mediated modulation of N- and P/Q- but not T-type CA²⁺ Channels
  QQ Sun, N Dale, Scotland ... 102

Inhibition of Myosin ATPASE by metal fluoride complexes
  S Park, K Ajtai, TP Burghardt,
  USA ... 103

Effects of caffeine on fluoride, calcium and phosphorus metabolism and calcified tissues in the rat
  X Chen, GM Whitford,
  USA ... 103-104

Isoflurane alters proximal tubular cell susceptibility to toxic and hypoxic forms of attack
  RA Zager, KM Burkhart,
  DS Conrad, USA ... 104-105

Stimulation by low concentrations of fluoride of the proliferation and alkaline phosphatase activity of human dental pulp cells in vitro
  O Nakade, H Koyama, J Arai,
  H Ariji, J Takada, T Kaku,
  Japan ... 105

Simulation study of AL³⁺ coordination in NaF-AL₃ mixtures: development of interaction potentials
  MJ Castiglione, M Wilson,
  PA Madden, England ... 106

Rat liver gtp-binding proteins mediate changes in mitochondrial membrane potential and organelle fusion
  JD Cortese, USA ... 106-107

Hyperkalemia risks in hemodialysed patients consuming fluoride-rich water
  A Nicolay, P Bertocchio, E Bargas,
  F Coudore, G Al Chahin,
  JP Reynier, France ... 107

DEFLUORIDATION
Optimization of fluoride removal from brackish water by electrodialysis
  Z Amor, S Malki, M Taky,
  B Bariou, N Mameri, A Elmidaoui
  Morocco, France, and Algeria ... 108

DIETARY FLUORIDE
Patterns of dietary fluoride supplement use during infancy
  SM Levy, MC Kiritsy, SL Slager,
  JJ Waren, USA ... 108-109

Concentrations of fluoride in wines from the Canary Islands
  OB Martinez, C Diaz, TM Borges,
  E Diaz, JP Perez, Spain ... 109

Fluoride contents in tea and soil from tea plantations and the release of fluoride into tea liquor during infusion
  KF Fung, ZQ Zhang, JWC Wong,
  MH Wong, China  ... 109-110

Fluoride supplements and fluorosis: a meta-analysis
  AI Ismail, RR Bandekar,
  USA ... 110-111

International fluoride supplement recommendations
  DW Banting, Canada ... 111

A re-examination of the pre-eruptive and post-eruptive mechanism of the anti-caries effects of fluoride: is there any anticaries benefit from swallowing fluoride?
  H Limeback, Canada ... 111-112

Fluoride supplements for young children: an analysis of the literature focusing on benefits and risks
  PJ Riordan, Australia ... 112-113

Chemical composition of bottled water in Saudi Arabia
  AI Alabdula’aly, MA Khan,
  Saudi Arabia  ... 113

ENVIRONMENTAL FLUORIDE POLLUTION
Application of a groundwater contamination index in Finland and Slovakia
  B Backman, D Bodis, P Lahermo,
  S Rapant, T Tarvainen,
  Finland and Slovakia ... 113-114

Pathological bone changes in the mandibles of wild red deer (Cervus Elaphus l.) exposed to high environmental levels of fluoride
  M Schultz, U Kierdorf,
  F Sedlacek, H Kierdorf,
  Germany and Czech Republic ... 114-115

Chemical composition of fresh snowfalls at Palmer Station, Antarctica
  TP DeFelice, USA ... 115

FLUORIDE ANALYSIS
Abnormally high fluoride levels in commercial preparations of 40 per cent silver fluoride solution: contraindications for use in children
  T Gotjamanos, V Orton,
  Australia ... 115-116

Indirect determination of trace amounts of fluoride in natural waters by ion chromatography: a comparison of on-line post-column fluorimetry and ICP-MS detectors
  MM Bayon, AR Garcia, JIG Alonso,
  A Sanz-Medel, Spain ... 116-117

Separation and determination of fluoride in plant samples
  HB Li, XR Xu, China ... 117

HEALTH/BIOLOGICAL EFFECTS
Changes in dental fluorosis and dental caries in newburgh and Kingston, New York
  JV Kumar, PA Swango, LL Lininger,
  GS Leske, EL Green, VB Haley,
  USA ... 117-118

Severe dental fluorosis in a Tanzanian population consuming water with negligible fluoride concentration
  KM Yoder, L Mabelya,
  VA Robison, AJ Dunipace,
  EJ Brizendine, GK Stookey,
  USA and Tanzania ... 118-119

The influence of toothbrushing frequency and post-brushing rinsing on caries experience in a caries clinical trial
  IG Chestnutt, F Schafer,
  APM Jacobson, KW Stephen,
  England and Scotland ... 119-120

Modern supragingival plaque control
  VJ Iacono, WA Aldredge, H Lucks,
  S Schwartzstein, USA ... 120

Effects of sodium fluoride on locomotor behavior and a few biochemical parameters in rats
  V Paul, P Ekambaram,
  AR Jayakumar, India ... 120-121

Effects of inorganic fluoride on renal excretion of fluid and sodium in diabetic rats
  BK Warren, MS Mozaffari,
  C Patel, USA ... 121-122

OSTEOPOROSIS: INTERVENTION OPTIONS [REVIEW]
  C Netelenbos, Netherlands ... 122

Acute lung injury after inhalation of water-proofing spray while smoking a cigarette
  Y Jinn, N Akizuki, M Ohkouchi,
  N Inase, M Ichioka, F Marumo,
  Japan ... 122-123

Oral hygiene: today’s view
  TG Needleman, England ... 123

DRINKING WATER FLUORIDATION AND BONE
  B Allolio, R Lehmann,
  Germany ... 123-124

Comparison of rates of change in bone density as measured by dual-energy x-ray absorptiometry and quantitative computed tomography in osteoporotic females treated with fluoride
  SM Hesseltine, DJ Baylink,
  CR Libanati, USA ... 124-125

Tissue necrosis after subgingival irrigation with fluoride solution
  S Sjostrom, S Kalfas, Sweden ... 125

The effect of fluoride treatment on bone mineral in rabbits
  D Chachra, CH Turner,
  AJ Dunipace, ;MD Grynpas,
  Canada and USA ... 125-126

Prevention and reversal of dental caries: role of low level fluoride
  JDB Featherstone, USA ... 126

Biological mechanisms of dental fluorosis relevant to the use of fluoride supplements
  PK DenBesten, USA ... 127

Endemic goitre in the absence of iodine deficiency in schoolchildren of the northern cape province of South Africa
  PL Jooste, MJ Weight, JA Kriek,
  AJ Louw, South Africa ... 127-128

Dental fluorosis and nutritional status of 6- to 11-year-old children living in rural areas of Paraiba, Brazil
  FC Sampaio, FR von der Fehr,
  P Arneberg, DP Gigante, A Hatloy
  Norway and Brazil ... 128

Evidence-based medicine and osteoporosis: a comparison of fracture risk reduction data from osteoporosis randomised clinical trials [review]
  PJ Meunier, France ... 129

Fluorosis of the primary dentition: what does it mean for permanent teeth?
  JJ Warren, MJ Kanellis,
  SM Levy, USA ... 129-130

Caries and fluorosis prevalence in communities with different concentrations of fluoride in the water
  IF Angelillo, I Torre I, CGA Nobile,
  P Villari, Italy ... 130-131

Caries-risk assessment [review]
  E Reich, A Lussi, E Newbrun,
  Germany ... 131

Dental caries in pre-school children: associations with social class, toothbrushing habit and consumption of sugars and sugar-containing foods - further analysis of data from the national diet and nutrition survey of children aged 1.5-4.5 years
  S Gibson, S Williams,
  England ... 131-132