We have conducted a study of the elimination kinetics of fluoride ions by a log linear regression analysis of plasma levels obtained during a bicarbonate hemodialysis session, with a dialyzer in polymercaprin for six patients with chronic renal failure. Using plasma fluoride levels of 35 patients studied for 20 months, we have validated these kinetics for hemodialysis with sodium bicarbonate, acetate-free biofiltration, hemodiafiltration with low flow rate and other dialyzers. Our results show that the decrease in plasma fluoride levels is statistically significant only after the first hour, and the fall reaches approximately 30% after a 4 h dialysis session. We propose that post-dialysis measurements of plasma fluoride are now not necessary if levels before dialysis are known.

Key words: Hemodialysis; Kinetics; Plasma fluoride level; Vichy St-Yorre water.

Reprints: A Nicolay, Hopital St Marguerite, F-13009 Marseille, France.

FLUORIDE 31(4),  1998, p 226	International Society for Fluoride Research
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